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《Chinese Journal of Critical Care Medicine》 2019-09
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Prognostic value of neutrophil CD64 and procalcitonin in patients with traumatic brain injury

Guo Wei-hong;Sun Qiong-qi;Chen Rui-juan;Department of Emergency,Haikou 120 Emergency Center;  
Objective To explore the prognostic value of neutrophil CD64 and procalcitonin (PCT)in patients with traumatic brain injury(TBI).Methods A total of 162 TBI patients admitted to Haikou 120 Emergency Center were divided into survival group(n=128) and death group (n=34) according to the prognosis of 28 days.Glasgow coma score(GCS)was used to divide the patients into mild group(n=106,9≤GCS≤15) and severe group (n=56,3≤GCS≤8).The changes of neutrophil CD64 and PCT on the 1st,3rd and 5th day in each group were compared.The value of neutrophil CD64 and PCT levels in predicting death in patients with TBI was analyzed using ROC curves. Pearson correlation analysis was used to analyze the correlation between neutrophil CD64 and PCT and GCS score in TBI patients.Results Neutrophil CD64(4.15±1.50 vs.2.40±0.85,6.63±2.10 vs. 3.25±0.96,8.14±2.70 vs.3.40±0.92)and PCT(ng/mL:1.40±0.73 vs.0.34±0.26,2.35± 1.28 vs.0.64±0.38,5.42±2.16 vs.0.58±0.34)levels in the death group on the 1st,3rd and 5th day were significantly higher than those in the survival group(P0.05),and neutrophil CD64 and PCT levels in the death group showed a rising trend(P0.05).Neutrophil CD64(3.90±1.42 vs.2.82± 0.94,6.12±1.85 vs.3.60±0.98,7.86±2.64 vs.3.53±0.87)and PCT(ng/mL:1.27±0.65 vs.0.50±0.32,2.04±1.25 vs.0.82±0.45,5.16±1.97 vs.0.73±0.38)levels in the severe group were significantly higher than those in the mild group on the 1st,3rd and 5th day(P0.05), and neutrophil CD64 and PCT levels in the severe group showed an increasing trend(P0.05).ROC curve showed that the AUC(0.924,95%CI 0.860-0.972)which combined neutrophil CD64 and PCT on the third day predicted the death of TBI patients was the largest,and its sensitivity and specificity were 92.8% and 87.2%,respectively.Correlation analysis showed that neutrophil CD64 and PCT were negatively correlated with GCS score in the death group (r=-0.752,-0.817,P 0.01),and neutrophil CD64 was positively correlated with PCT(r=0.684,P0.01).Conclusion Neutrophil CD64 and PCT are correlated with the severity of TBI patients,and the combination of neutrophil CD64 and PCT on the third day is of high value in predicting the prognosis of TBI patients.
【Fund】: 海南省醫藥衛生科研基金項目(17A200293)
【CateGory Index】: R651.15
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 DENG Shui-xiang;MAO Yi-hu;CAO Tong-wa;Intensive Care Unit,Affiliated Huashan Hospital,Fudan University;;The dynamic change of procalcitonin and its relation to prognosis in simple brain trauma patients[J];中國急救醫學;2015-10
2 XUE Jing;MA Yi-ping;YU Yang;L Li-xia;ZHANG Xin;LIANG En-he;Department of Laboratory Medicine,Huanhu Hospital of Tianjin;;Prognostic value of serum procalcitonin in patients with severe traumatic brain injury[J];中華創傷雜志;2013-12
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 Guo Wei-hong;Sun Qiong-qi;Chen Rui-juan;Department of Emergency,Haikou 120 Emergency Center;;Prognostic value of neutrophil CD64 and procalcitonin in patients with traumatic brain injury[J];中國急救醫學;2019-09
2 YUAN Hua;LIU Long;PFNG Yuan;Intensive Care Unit,the First People's Hospital of Kunshan;;The dynamic changes of procalcitonin and interleukin-6 in brain trauma patients and its clinical significance[J];徐州醫科大學學報;2017-08
3 Yu Zhixin;Ji Musen;Hu Xiulan;Yan Jun;Jin Zhaochen;Department of Critical Care Medicine,Affiliated People's Hospital of Jiangsu University;;Value of procalcitonin on predicting the severity and prognosis in patients with early ARDS:a prospective observation study[J];中華危重病急救醫學;2017-01
4 Ma Junyu;Wang Shupeng;Chen Desheng;Duan Jun;Li Chen;Li Gang;Department of Surgery Intensive Care Unit,China-Japan Friendship Hospital;;The prognostic value of serum procalcitonin on severity of illness in non-sepsis critically ill patients[J];中華危重病急救醫學;2016-08
5 HUANG Zhongguo;Department of Laboratory, the Maternal and Child Health Hospital in Ziyang District of Yiyang City in Hu'nan Province;;The relationship between the procalcitonin level and liver function in patients with hepatitis and liver cirrhosis[J];中國現代醫生;2014-35
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 ZHANG Xiaofan;LI Li;GAO Yanxia;LU Guangping;HUANG Li;DUAN Guoyu;Department of Emergency,the First Affiliated Hospital of Zhengzhou University;;The dynamic change and clinical significance of procalcitonin in acute paraquat intoxication patients[J];臨床急診雜志;2014-10
2 FEI Ai-hua,PAN Shu-ming,LIU Ming,CHEN MiaoEmergency Center,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China;Value of procalcitonin to the prediction of multiple organ dysfunction syndrome in patients with brain injury[J];中華實用診斷與治療雜志;2011-09
3 LIN Yan,SHAO Qi-hui,AN Yi(Tongji Hospital,Tongji University,Shanghai 200065,China);Nosocomial Infection in Neuro-Intensive Care Unit[J];中華醫院感染學雜志;2007-12
4 Jia Conglin,Si Zhiping,Tong Yunlong,et al.Department of Neurosurgery,The People's Hospital of Fenghua City,Zhejiang 315500,China;The Relationship Between the Dynamic Change of High-sensitivity C-reactive Protein,IL-1β,IL-6 and the Prognosis of the Patients with Acute Traumatic Brain Injury[J];醫學研究雜志;2007-11
5 YANG Bo jie, ZHAO Da li △ , LI Sheng chang, XU Qi wu (Department of Neurosurgery,Huashan Hospital,Fudan University,Shanghai, 200040; △ Department of Neurosurgery,The First Hospital of Tongyu,Tongyu, 137200);Evaluation of the Prognosis of Acute Comatose Patients by Evoked Potentials[J];復旦學報(醫學科學版);2001-05
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